Vegetable compounds may go beyond prevention

Research at the Texas Agricultural Experiment Station has found that diindolylmethane (DIM), a byproduct of the compound indole-3-carbinol, which is formed in broccoli, cabbage, turnips and mustard greens, may be helpful in treating as well as preventing cancer. Clinical trials of the compounds as a cancer treatment are planned to take place at M D Anderson Cancer Center in Houston.

Steve Safe MD and colleagues studied cancer-preventing compounds found in cruciferous vegetables and discovered that they target a protein known as PPAR gamma, which is highly active in fat cells. PPAR is also overexpressed in tumors, therefore compounds that prevent cancer may also help treat tumors. Read more...

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